Description
Testosterone, Free, Direct tests measure the concentration of circulating testosterone not bound to proteins like sex hormone-binding globulin (SHBG) and albumin. These proteins attach to testosterone in the blood, making it unavailable to body tissues. Testosterone, Free, Direct tests measure the amount of testosterone that is accessible to the body’s tissues. The test is used to diagnose and follow the course of conditions related to excessive or insufficient testosterone, such as pituitary and testicular disorders, including infertility or Klinefelter’s syndrome. It is also used to detect early-onset puberty in males, delayed puberty in females, and polycystic ovary syndrome. It is also used to aid in evaluating causes of erectile dysfunction, or to measure testosterone levels in people taking hormone replacement therapy. Understanding the amount of free testosterone in the body helps to ensure that individuals have the right amount of the hormone for optimal health.